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Talisman of Ascension
Sylas
Annie
Syndra
Ashe
Lee Sin
Gnar
- Talisman is currently strongest Artifact in the game, works well on every Carry and Bruisers overall
- High synergy with Hero Augments (especially Garen, Shen, Yorick)
- Stack with itself, so multiple Talisman = overpowered
Suspicious Trench Coat
Udyr
Ornn
Lissandra
Sylas
Galio
Annie
Yasuo
Thresh
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- Units that split with Suspicious Trench Coat keep the starting mana, even from items like Protector's Vow
- Very nice on Udyr because of his passive the clones can't get bursted down
- Very good with Bruisers, because the clones spawn with higher HP and profit from Bruiser trait
- Strong opener with Yasuo Fated Buff, because the clones spawn with the bonus shield
Wit's End
Bard
Volibear
Lissandra
- Mainly intended for Bard Carry
- Healing is based off all of magic damage, so it can act as a substitute to Gunblade
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Innervating Locket
Annie
Sylas
Galio
Ornn
Amumu
- Good on high HP tanky Frontliner
- Has positive synergy with other Artifacts like Forbidden Idol and Talisman of Ascension
- Works well with Garen / Yorick Hero Augment
Mittens
Lee Sin
Wukong
Udyr
Volibear
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- Mittens is mainly a statstick
- Good for Melee carries, especially for Movement Speed
- Can work on same ranged carries like Irelia
Lightshield Crest
Galio
Annie
Ornn
Thresh
Amumu
- Lightshield is good on units with high defensive stats (Stoneplate, Behemoth etc)
- Galio gains bonus Armor/MR during cast, making shield stronger
- Mainly used as a tempo item
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Horizon Focus
Nautilus
Lux
Lissandra
Annie
- Horizon Focus is preferred on high CC units like Nautilus / Annie
- Can also put it on caster units like Lux / Lissandra
- Has positive synergy with Silvermere Dawn, Tattoo of Force and Eternal Winter
- Gets countered by CC immunity (QSS/Silverveil)
Spectral Cutlass
Kayn
Lee Sin
Wukong
Lissandra
Qiyana
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- Spectral Cutlass is good on units with high single target burst and cast early
- Units that teleport will take aggro from enemy backline, be careful!
- Some units like Yone, Tristana, Udyr etc can return if their cast is at the same time as the teleport
Unending Despair
Ornn
Illaoi
Rakan
- Unending Despair is mainly used as a tempo item, it's too weak to build a comp around it
- Good on Ornn/Illaoi/Rakan because they have high shields and make use of the item stats
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Silvermere Dawn
Sett
Wukong
Lee Sin
Riven
Kayn
Kha'Zix
- You want Silvermere on units that either cast a lot due to damage taken or have very impactful abilities with AD scaling
- Has synergy with Horizon Focus
- Can work on Irelia, but the low Attack Speed interferes heavily with her kit
- Good on Khazix / Malphite (Aoe Attack) in early game
Forbidden Idol
Tahm Kench
Rakan
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- Forbidden Idol works best on Tahm, especially if you have a second Forbidden Idol or a Talisman of Ascension
- Can give it to Rakan in late game, since he has a very large shield that doesn't last long anyways
Fishbones
Ashe
Irelia
Xayah
Kog'Maw
- Fishbones works best on Ashe, because she can reach entire map and random shots to enemy backline will have maximum Sniper value
- Can be good on Kog'Maw, since he can reach enemy backline right from the start
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Lich Bane
Lillia
Kindred
Syndra
Teemo
- Lich Bane is good on low mana cost carries, especially Kindred/Teemo and later Syndra/Lillia
Seeker's Armguard
Sylas
Annie
Lissandra
Syndra
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- Seeker's Armguard can be put on your main DPS in early game, since it gives very good stats
- Later you can give it to Sylas/Annie in frontline or give it to AP carry like Syndra
- Has Synergy with Shen Hero Augment
Luden's Tempest
Azir
Lissandra
Hwei
Caitlyn
Kog'Maw
Alune
Kobuko
- Luden's Tempest is good with very high single target burst to get maximum value
- The bonus damage can proc of itself, leading to a snowball effect
- Caitlyn and Kobuko 3 Star can be good with Luden, but it's not a reliable build for ranked
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Blighting Jewel
Teemo
Syndra
Morgana
- Blighting Jewel works best on Teemo, since his poison will constantly proc the effect
- Morgana and Syndra can work with this item, but they are much worse holders compared to Teemo
Rapid Firecannon
Qiyana
Xayah
Lissandra
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- The only unit that gets good use out of Rapidfire Cannon is Qiyana
- A lot of units have bad interactions with increased range
- Units that want increased range are usually better off taking Sniper's Focus
- If you get the item in late game you can give it to Xayah/Lissandra etc
Prowler's Claw
Kayn
Lee Sin
Wukong
- Prowler's Claw works best on strong melee carries like Kayn, Lee Sin or Wukong
- Unfortunately the dash doesn't always reset the aggro from backline carries, which can result in a bad fight
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Corrupt Vampiric Scepter
Irelia
Gnar
- Corrupt Vampiric Scepter works best on Irelia and Gnar, since they both receive a lot of AD from their passive and don't depend on their ability
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