Disclaimer
As this set is still on PBE, changes are bound to happen. It should still be correct for a while after it gets live, but a more detailled guide will be made.
Also, there's currently no option to define a unit as the Headliner, which would help make it more precise. In the meantime, I put units to fit the comp, but of course you can adapt depending on which trait your Headliner gives you.
Late game
























Early comp








If you can, bring in Hearsteel to stock some gold. Unlike set 9's and 9.5's Piltover, you can bring it anytime you want since it will always give you the loot after 4 PVP rounds. If you can get Yone as your Headliner, prefer Heartsteel or Edgelord as his trait bonus, you'll get Qiyana for a Crowd Diver in late game anyway.
Double Titan helps him stack a lot of damage and resistances, especially if you've got the augment that allows them to stack up to 40. Every time Yone casts, he gets stacking move speed and Omnivamp which scales on AP, meaning he'll get insane heals at the ends of the rounds. Sterak will make him a bit bulkier, but if you put your hands on one, a Death Defiance will be even better. A Bloodthirster will also do the trick.